Postdoctoral Researcher in Immunology and Virology

This postdoctoral position is hosted at the Institut Pasteur in Paris within Dr. Lisa Chakrabarti’s team and the Organ-on-Chip Platform led by Dr. Samy Gobaa, with employment through the BIOEPAR joint research unit at INRAE-Oniris. The researcher will spearhead the FluOrganoVax project, aiming to establish a porcine lymph-node-on-chip model to simulate immune responses and assess vaccine formulations without relying on animal testing. Key expectations include culturing immune cells, optimizing microfluidic devices, conducting flow cytometry and assays, and publishing findings in scientific journals. The role offers an interdisciplinary environment spanning immunology, virology, and bioengineering.

• Develop and fabricate a porcine lymph-node-on-chip model incorporating primary porcine immune cells.
• Optimize device perfusion, media, and culture conditions to maintain model viability and stability.
• Characterize cellular composition and immune responses using flow cytometry, confocal microscopy, and ELISA.
• Perform functional assays including ELISpot, intracellular cytokine staining, and virus neutralization.
• Analyze experimental data using statistical tools and software, interpret findings, and draft scientific publications.