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Neuroscience● OpenPostdocPreview

Research Associate in Modelling Friedreich's Ataxia Using iPSC-derived Neurons

Investigate Friedreich's ataxia mechanisms and therapeutics using human iPSC-derived neuronal models at SITraN.

Best for:Best for postdoctoral researchers with expertise in human iPSCs, neuronal differentiation, and translational neuroscience.

University of Sheffield · Sheffield, United Kingdom · R2 · Recognised researcher
More professors at University of Sheffield
Friedreich's ataxiaInduced pluripotent stem cellsNeuronal modelsTranslational neuroscienceElectrophysiologyNeurodegeneration
This is a postdoc position — not a PhD studentship.
Deadline
Nov 1, 2026
18 days
Funding
Salaried
£38.8k–£47.4k/yr
Start date
flexible
Full-time
Location
Sheffield
United Kingdom

Overview

The University of Sheffield invites applications for a Postdoctoral Research Associate position within the Division of Neuroscience at the School of Medicine and Population Health. Working at the Sheffield Institute for Translational Neuroscience (SITraN), the successful candidate will join a multidisciplinary team to study cellular mechanisms underlying Friedreich’s ataxia using human induced pluripotent stem cell (iPSC) and neuronal models. The role involves designing and executing experimental studies, analyzing complex data, contributing to scientific publications, and supporting less experienced researchers. Applicants are expected to have a strong background in laboratory-based neuroscience or related biological sciences alongside expertise in advanced cellular techniques.

Research AssociatePostdociPSCNeuronal differentiationNeuroscienceFriedreich's ataxiaElectrophysiologySITraN

What you'll do

  • Plan and execute experimental studies utilizing human iPSC-derived neuronal models
  • Analyze, interpret, and document experimental data to support translational neuroscience objectives
  • Contribute to the development, optimization, and troubleshooting of research methodologies
  • Apply techniques including iPSC culture and differentiation, immunocytochemistry, fluorescence microscopy, patch-clamp electrophysiology, molecular biology, and RNA sequencing
  • Contribute to the drafting of scientific manuscripts, presentations, and future research funding applications
  • Provide practical guidance, training, and support to students and junior researchers within the laboratory

Requirements

Degree required: PhD in Neuroscience, Biological Sciences, Biomedical Sciences, or a related subject

Language: English

Instruction: English

Required skills
  • Demonstrable experience in laboratory-based research
  • Ability to independently plan and execute research projects within a collaborative environment
  • Strong background in molecular or cellular biology techniques
Nice to have
Hands-on experience with human iPSC modelsExpertise in neuronal differentiation protocolsExperience with immunocytochemistry and fluorescence microscopyProficiency in whole-cell patch-clamp electrophysiologyExperience with RNA sequencing and molecular analysis

Funding & terms

Type
Salaried
Amount
£38.8k–£47.4k/yr
Duration
—
Programme
University of Sheffield
University of Sheffield

How to apply

Deadline: 2026-11-01

Candidates must submit their application through the external job portal link provided. Ensure all requested profile details and employment history are fully completed before the deadline.

Documents required
  • CV
  • Cover letter
↗Apply via form
ML
Prof.
Matt Livesey
School of Medicine & Population Health
Lab
Sheffield Institute for Translational Neuroscience (SITraN)
University of Sheffield
United Kingdom
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