Postdoctoral Research Associate
Join the Nicholson Lab at Queen Mary University of London to investigate epigenetic heterogeneity in glioblastoma.
Best for:Ambitious researchers in cancer or molecular biology with expertise in mammalian cell culture and an interest in single-cell epigenomics.
Overview
The Nicholson Lab at the Blizard Institute, Queen Mary University of London, is seeking an ambitious Postdoctoral Research Associate to join their newly established team. This role focuses on understanding how epigenetic heterogeneity drives treatment resistance and recurrence in glioblastoma using patient-derived models, cerebral organoids, and single-cell epigenomics. As the first postdoc in the lab, the successful candidate will have significant intellectual ownership over the experimental programme and the opportunity to shape the group's research direction. The position offers a 42-month appointment, providing a stable environment to conduct longitudinal studies and develop a strong profile in cancer research.
What you'll do
- Lead an experimental programme investigating epigenetic subpopulations in glioblastoma.
- Establish longitudinal treatment models using patient-derived glioma-initiating cells.
- Generate single-cell DNA methylation and transcriptomic libraries.
- Evaluate therapies targeting resistant states using cell and organoid models.
- Analyze and interpret complex experimental data.
- Supervise students and contribute to the lab's research culture.
- Disseminate research findings through first-author publications and conference presentations.
Requirements
Degree required: PhD in cancer biology, molecular biology, or a related discipline.
Language: English proficiency required.
Instruction: English
Publications: Not explicitly specified, but expected to produce first-author publications.
- Substantial hands-on experience in mammalian cell culture.
- Strong background in molecular and cellular biology techniques.
- Ability to plan and deliver independent research projects.
- Capacity to interpret and communicate scientific data effectively.
- Must hold or be near completion of a PhD in a relevant field.
Funding & terms
How to apply
Deadline: 2026-10-22
Interested candidates should submit their application through the university's official portal. Ensure all required documentation is attached to support your candidacy.
- CV
- Cover letter
- Research statement
Contact
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