PhD Monitor
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Computational Biology● OpenOpen until filledPreview

PhD Position in Computational Methods for Digital Twins of Embryonic Development & Disease

Develop scalable algorithmic infrastructure and simulation environments for digital twins of biological systems.

Best for:Best for candidates with a strong background in computer science or applied mathematics who are eager to apply numerical methods and machine learning to biological systems.

ETH Zürich · Zurich, Switzerland · R1 · First-stage researcher
More professors at ETH Zürich
Digital TwinsComputational ModelingMachine LearningParameter EstimationUncertainty QuantificationSystems Biology
Deadline
Until filled
rolling
Funding
Salaried
Competitive ETH doctoral salary
Start date
flexible
Full-time
Location
Zurich
Switzerland

Overview

The Computational Biology Group at ETH Zürich is seeking a PhD candidate to advance the development of digital twins for embryonic development and reproductive health. The project focuses on creating robust algorithmic infrastructure to handle high-dimensional, nonlinear models and noisy biological data. The successful applicant will work at the intersection of machine learning, scientific computing, and biology to build scalable simulation tools. This role involves close collaboration with experimentalists and clinicians to apply these models to real-world challenges, such as IVF treatment planning.

Computational BiologyScientific ComputingPhysics-Informed Neural NetworksSimulationBioinformaticsAlgorithm Development

What you'll do

  • Develop and benchmark algorithms for parameter estimation and uncertainty quantification.
  • Implement and optimize simulation environments with a focus on scalability and reproducibility.
  • Apply computational methods to imaging-based models of tissue development and hormonal cycles.
  • Collaborate with experimentalists and clinical partners to integrate real-world data into models.
  • Contribute to the group's open-source software projects.
  • Publish research findings in peer-reviewed journals and present at international conferences.
  • Participate in teaching activities within the department.

Requirements

Degree required: Master's degree in Computer Science, Computational Science and Engineering, Applied Mathematics, Physics, or a related field.

Degree offered: PhD

Language: Good written and spoken English.

Instruction: English

Required skills
  • Strong programming proficiency in Python, Julia, or C++.
  • Experience in writing clean, well-tested, and maintainable code.
  • Solid foundation in numerical methods, optimization, or statistical inference.
  • Demonstrated interest in applying quantitative methods to biological or biomedical problems.
Nice to have
Experience with PDE-based simulations or finite element methods.Familiarity with high-performance computing environments.Proficiency in deep-learning frameworks such as PyTorch or JAX.

Funding & terms

Type
Salaried
Amount
Competitive ETH doctoral salary
Duration
not specified
Programme
ETH Zürich
ETH Zürich

How to apply

Applications must be submitted exclusively through the official ETH Zürich online portal. Please prepare a letter of motivation, your CV, academic transcripts, and contact details for two referees.

Documents required
  • Letter of motivation
  • CV
  • BSc diploma and transcripts
  • MSc diploma and transcripts
  • Contact details of 2 referees
↗Apply on site

Contact

DI
Lab
Computational Biology Group
ETH Zürich
Switzerland
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