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Doctoral Position in Evolutionary Genomics (Experimental/Computational)

Join a leading evolutionary genomics group to investigate the molecular evolution of organs in vertebrates using cutting-edge experimental and computational methods.

Best for:Best for candidates with a strong background in genomics, bioinformatics, or molecular biology who are eager to bridge experimental and computational research.

Heidelberg University · Heidelberg, Germany · R1 · First-stage researcher
More professors at Heidelberg University
Evolutionary GenomicsGene ExpressionComparative GenomicsBioinformaticsSpatial TranscriptomicsMolecular Evolution
Deadline
Until filled
rolling
Funding
—
3 years, with possible extension
Start date
immediately
Full-time
Location
Heidelberg
Germany

Overview

The evolutionary genomics group led by Henrik Kaessmann at Heidelberg University is seeking a highly motivated PhD candidate to join their research team. The lab focuses on the origins and molecular evolution of organs in mammals and other vertebrates, with a specific emphasis on gene expression and regulatory mechanisms. Successful applicants will work on projects that integrate experimental data generation—such as long-read spatial transcriptomics—with advanced computational and deep-learning analyses. The position offers a collaborative, international environment within the Center for Molecular Biology (ZMBH) in Heidelberg. Candidates will have the opportunity to tailor their research focus based on their individual expertise and interests.

PhD positionEvolutionary BiologyGenomicsComputational BiologyMolecular BiologyHeidelberg UniversityZMBH

What you'll do

  • Develop and execute research projects focused on the evolution of gene expression and regulatory mechanisms.
  • Generate high-quality experimental datasets using cutting-edge techniques such as long-read spatial transcriptomics.
  • Perform advanced computational and bioinformatics analyses, including the application of deep learning models.
  • Collaborate within small, interdisciplinary teams of experimental and computational researchers.
  • Contribute to the functional characterization of evolutionary changes using organoid or mouse models.
  • Participate in the vibrant, international research community at the ZMBH and the broader Heidelberg research hub.

Requirements

Degree required: Master Degree or equivalent

Degree offered: PhD

Language: English (working language of the institute)

Instruction: English

Required skills
  • Strong academic background in evolutionary biology, genomics, or a related field.
  • Aptitude for experimental molecular biology or genomics techniques.
  • Proficiency in computational or bioinformatics data analysis.
  • Ability to work collaboratively in an international team environment.
Nice to have
Experience with single-cell RNA-seq or ATAC-seq data analysis.Familiarity with deep learning or AI-driven bioinformatics approaches.Experience with CRISPR-based functional genomics or synthetic genomics.Prior experience with organoid or mouse model systems.
Eligibility
  • Must hold a Master's degree or equivalent at the time of appointment.

Funding & terms

Type
Unknown
Amount
—
Duration
3 years, with possible extension
Programme
—

How to apply

Deadline: 2026-11-30 (Europe/Paris) · open until filled

Interested candidates should submit a CV, a statement of research interests, and the contact details of three references via email to Henrik Kaessmann. Applications are reviewed on a rolling basis until the positions are filled.

Documents required
  • CV
  • Statement of research interests
  • 3 reference letters
✉Apply by email

Contact

HK
Prof.
Henrik Kaessmann
Center for Molecular Biology
Lab
Evolutionary Genomics Group
Heidelberg University
Germany
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