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Biological Sciences● OpenPreview

PhD Studentship: Engineering Gene Drives for Pest Insect Suppression

Develop advanced CRISPR-based gene drive technologies to sustainably suppress agricultural pest insect populations.

Best for:Best for biology graduates with strong molecular skills and an interest in CRISPR technology and agricultural pest control.

University of East Anglia · South East England, United Kingdom · R1 · First-stage researcher
More professors at University of East Anglia
Gene drivesCRISPR technologySynthetic biologyInsect pest managementFunctional genomicsPopulation modeling
Deadline
Nov 30, 2026
38 days
Funding
Salaried
£21.8k/yr
Start date
2027-10-01
Fixed-term
Location
South East England
United Kingdom

Overview

The University of East Anglia invites applications for a fully funded 4-year PhD studentship focused on engineering gene drives for the suppression of the Mediterranean fruit fly (medfly) and other agricultural pests. Based within the School of Biological Sciences as part of the Norwich Research Park Biosciences Doctoral Training Programme, the project involves building, testing, and optimizing split-drive pipelines through interdisciplinary collaboration. Candidates will gain cutting-edge expertise in CRISPR design, synthetic biology, single-nucleus transcriptomics, and population modeling, complemented by placement opportunities at Keele and Imperial College London. The selected researcher will be expected to conduct independent experimental work, optimize phenotyping protocols, and translate findings toward field-deployable biosecurity solutions.

PhD studentshipCRISPRGene driveMedflyTranscriptomicsSynthetic biologyBiological sciencesNorwich Research Park

What you'll do

  • Design and construct split-drive systems to evaluate parameters governing gene drive performance.
  • Perform CRISPR editing, cloning, and single-nucleus transcriptomics to analyze genetic components.
  • Establish robust quantitative phenotyping protocols to measure insect fitness and drive efficiency.
  • Isolate optimal promoters, guides, and targets while mitigating resistance alleles and shadow drive.
  • Complete a three-month professional internship placement during the course of the doctoral study.
  • Collaborate with partner institutions including Keele University and Imperial College London.
  • Disseminate research outcomes through scientific publications and presentations.

Requirements

Degree required: Bachelors (Honours) 2:1 or UK equivalence

Degree offered: PhD

Language: English; IELTS 6.5 overall with minimum 6 in each category

Instruction: English

Required skills
  • Background in biological sciences or a closely related discipline
  • Demonstrated academic excellence at the undergraduate level
  • Aptitude for molecular biology and genetic engineering techniques
  • Interest in interdisciplinary research encompassing bioinformatics and modeling
Nice to have
Prior laboratory experience with CRISPR or gene editing technologiesExperience in handling insects or agricultural pestsFamiliarity with single-nucleus transcriptomics or bioinformatics pipelinesBackground in population modeling or quantitative phenotyping
Eligibility
  • Open to candidates meeting standard UK doctoral training admission criteria without regard to background.

Funding & terms

Type
Salaried
Amount
£21.8k/yr
Duration
4 years
Programme
Norwich Research Park Biosciences Doctoral Training Partnership PhD DTP
Norwich Research Park Biosciences Doctoral Training Partnership

How to apply

Deadline: 2026-11-30

Applicants must complete their application through the university's postgraduate research application portal. Candidates must use the bespoke templates provided on the NRPDTP website for their Personal and Research statements. Shortlisted applicants will be invited for interviews following initial review.

Documents required
  • CV
  • Personal statement
  • Research statement
  • Academic transcripts
  • Reference letters
↗Apply on site
TC
Prof.
Tracey Chapman
School of Biological Sciences
Lab
Norwich Research Park Biosciences Doctoral Training Programme
University of East Anglia
Norwich Research Park Biosciences Doctoral Training Partnership PhD DTPUnited Kingdom
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