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Postdoctoral Research Scientist in Mitochondrial Biology

Join the CONTROL-MITO team to develop chemical-genetic toolkits for engineering mitochondrial DNA.

Best for:Best for postdoctoral researchers with a PhD in mitochondrial or cell biology and hands-on experience in mammalian cell culture and assay development.

CRUK Scotland Institute · Glasgow, United Kingdom · R2 · Recognised researcher
More professors at CRUK Scotland Institute
mitochondrial biologychemical geneticscellular metabolismbioengineeringmitochondrial DNA
This is a postdoc position — not a PhD studentship.
Deadline
Nov 20, 2026
30 days
Funding
Salaried
£39.3k–£45.5k/yr
Start date
flexible
Full-time
Location
Glasgow
United Kingdom

Overview

The CRUK Scotland Institute is seeking a highly motivated Postdoctoral Research Scientist to join the CONTROL-MITO project within the ARIA-funded Precision Mitochondria programme. Based in Glasgow, the researcher will act as the team's mitochondrial biologist, testing novel chemical-genetic tools and leading the mitochondrial phenotyping of bioengineered human cell lines. The position involves collaborating with multidisciplinary academic and industry partners across the UK to advance programmable physiology. Responsibilities include assessing mitochondrial bioenergetics, monitoring genome maintenance, and contributing to consortium meetings and scientific publications.

PostdoctoralMitochondriaCell BiologyLC-MSMetabolomicsCRUKARIA

What you'll do

  • Measure the impact of chemical probes on mitochondrial bioenergetics and metabolism using respirometry and LC-MS.
  • Investigate mitochondrial morphology, function, and quality control in bioengineered cells via fluorescence confocal microscopy, flow cytometry, and proteomics.
  • Monitor mitochondrial genome maintenance and expression in bioengineered cell lines.
  • Collaborate with core facilities including Metabolomics, Advanced Imaging, and Proteomics.
  • Engage with multidisciplinary teams to drive the Precision Mitochondria programme forward.
  • Present findings at consortium and ARIA meetings, prepare manuscripts for publication, and help supervise junior researchers and students.

Requirements

Degree required: PhD in mitochondrial/cell biology, or a closely related discipline

Language: English

Instruction: English

Required skills
  • Hands-on experience of mammalian cell culture
  • Ability to work independently and manage experimental workflows
  • Open, rigorous, and reproducible approach to scientific research
  • Excellent communication and teamwork skills in a multidisciplinary environment
Nice to have
Familiarity with chemical genetic tools such as degron tags or chemically induced proximity systemsExperience in quantifying mitochondrial gene maintenance and expressionExperience with mitochondrial quality control assays, including mitophagy reporters and stress responsesExperience with mass spectrometry metabolomics or stable isotope tracing

Funding & terms

Type
Salaried
Amount
£39.3k–£45.5k/yr
Duration
Fixed up to 6 years, subject to successful review at Year 3
Programme
Precision Mitochondria Programme
ARIA

How to apply

Deadline: 2026-11-20

All applications must be submitted via the online application button provided on the source portal. Candidates are encouraged to apply promptly as suitable candidates may be interviewed before the closing date.

Documents required
  • CV
↗Apply on site

Contact

TM
Prof.
Tom MacVicar
Mitochondrial Biology
Lab
CONTROL-MITO
CRUK Scotland Institute
Precision Mitochondria ProgrammeUnited Kingdom
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