Leveraging Heterogeneity in T Cell Receptor Signaling to Enhance Adoptive Cell Therapy
A PhD opportunity to explore T cell receptor signaling diversity for improved adoptive cell therapies in cancer treatment.
Best for:Best for immunology or cell biology PhD students interested in translational research and adoptive cell therapies for cancer.
Overview
This PhD position focuses on understanding the heterogeneity of T cell receptor signaling to develop more effective adoptive cell therapies. The project aims to uncover how variations in signaling pathways influence therapeutic outcomes, particularly in cancer treatment. The successful candidate will conduct research within a collaborative academic environment, contributing to advancements in immunotherapy. The work involves experimental biology, cellular analysis, and translational research to bridge fundamental discoveries with clinical applications. Applicants should have a strong background in immunology, cell biology, or a related field and a passion for translational research.
What you'll do
- Investigate the heterogeneity of T cell receptor signaling pathways to identify key factors influencing therapeutic efficacy in adoptive cell therapies.
- Conduct experimental research involving cell culture, molecular biology techniques, and advanced imaging to analyze signaling dynamics.
- Develop and validate novel experimental models to study the impact of signaling heterogeneity on immune cell function.
- Collaborate with interdisciplinary teams to translate research findings into potential clinical applications.
- Publish research findings in high-impact scientific journals and present results at national and international conferences.
- Contribute to the supervision of undergraduate or master’s students involved in related research projects.
Requirements
Degree required: Master's degree in Immunology, Cell Biology, Biochemistry, or a related field
Degree offered: PhD
Language: French and English proficiency; English is the primary language of work
Instruction: French and English
- Strong background in molecular biology and cell culture techniques
- Experience with flow cytometry, immunofluorescence, or related imaging techniques
- Familiarity with bioinformatics tools for data analysis
- Proficient laboratory skills in handling cell lines and primary cells
- Ability to design and execute experimental protocols
- No specific nationality restrictions
- Open to applicants with prior research experience in immunology or related fields
- No age restrictions
Funding & terms
How to apply
Deadline: 2026-11-30
Applicants should submit their CV, a cover letter outlining their research interests and motivation, and a research proposal to the relevant doctoral school or laboratory. Additional documents may be requested based on the evaluation of initial submissions.
- CV
- Cover letter
- Research proposal
- Transcripts of academic records (Bachelor’s and Master’s degrees)
Create a free profile to unlock your personal match score, the full requirements, funding details and how to apply — in English or Persian.