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Organic Chemistry & Biochemistry● Open★ EU-FUNDEDPreview

PhD Position in Bioorthogonal & Supramolecular Chemistry

Explore mechanical bonds and rotaxanes to control bioorthogonal reactions in cellular environments.

Best for:Best for chemistry graduates with a strong organic synthesis background interested in supramolecular chemistry and chemical biology.

Instituto de Productos Naturales y Agrobiología · La Laguna, Spain · R1 · First-stage researcher
More professors at Instituto de Productos Naturales y Agrobiología
supramolecular chemistrybioorthogonal reactionsrotaxanesorganic synthesischemical biologycontrolled drug release
Deadline
Oct 31, 2026
16 days
Funding
Salaried
48 months
Start date
2027-02-01
Full-time
Location
La Laguna
Spain

Overview

The Instituto de Productos Naturales y Agrobiología offers a fully funded 48-month doctoral position within the Molecular Sciences department. The researcher will investigate the control of bioorthogonal reactions through mechanical bonds using rotaxanes and interlocked molecular architectures. Key activities include chemical synthesis, structural characterization, kinetic evaluation, and cellular testing for targeted drug release or sensing applications. The successful candidate is expected to conduct rigorous laboratory research, synthesize complex molecular systems, and advance supramolecular chemistry methodologies.

PhD positionorganic chemistrysupramolecular chemistryrotaxanesbioorthogonal chemistrychemical synthesisNextGenerationEUIPNA-CSIC

What you'll do

  • Synthesize interlocked molecules, rotaxanes, and their non-interlocked analogues
  • Characterize newly synthesized chemical compounds using standard analytical techniques
  • Test and evaluate the reaction kinetics of designed bioorthogonal systems
  • Analyze the structural influence of macrocycles surrounding molecular axles
  • Evaluate responsive rotaxanes in cellular environments for controlled drug release and sensing

Requirements

Degree required: Master Degree or equivalent in Chemistry or related discipline

Degree offered: PhD

Language: English; excellent proficiency required

Instruction: English

Required skills
  • Strong background in organic synthesis and chemical laboratory techniques
  • Experience with the characterization of organic molecules
  • Familiarity with supramolecular chemistry principles
  • Capacity to conduct independent experimental research and problem solving
Nice to have
Prior research experience involving interlocked molecules or rotaxanesBackground in bioorthogonal chemistry or chemical biology applicationsDemonstrated experience in kinetic analysis of chemical reactions
Eligibility
  • Applicants must hold a master degree or equivalent qualification accepted for doctoral studies

Funding & terms

Type
Salaried
Amount
—
Duration
48 months
Programme
NextGenerationEU
EU-FUNDEDNextGenerationEU

How to apply

Deadline: 2026-10-31 (Atlantic/Canary)

Interested applicants should submit their application materials via email directly to the contact address provided, ensuring the subject line references the specific PhD position in bioorthogonal and supramolecular chemistry.

Documents required
  • CV
  • Cover letter
  • Transcripts
✉Apply by email

Contact

RC
Prof.
R. Carrillo
Molecular Sciences
Lab
IPNA-CSIC
Instituto de Productos Naturales y Agrobiología
NextGenerationEUSpain
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